Anti-MTMR4 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9NYA4
Gene Id	9110
Gene Symbols	MTMR4
Protein Name / Synonyms	MTMR4 (C-term)
Clonality	Polyclonal
Preparation	This MTMR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1155-1187 amino acids from the C-terminal region of human MTMR4.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MTMR, a member of the myotubularin family, encodes an intracellular protein of 1,195 amino acids, and shares approximately 47% sequence identity with MTMR3, spiking to over 70% identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.

Specificity

Other Names

MTMR4; KIAA0647; ZFYVE11; Myotubularin-related protein 4; FYVE domain-containing dual specificity protein phosphatase 2; Zinc finger FYVE domain-containing protein 11

NCBI Accession #

NP_004678.3

Other Accession #

NM_004687

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

133353

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	The anti-MTMR4 Pab (Cat# 102-16950) is used in Western blot to detect MTMR4 in mouse heart cell lysate.
	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with MTMR4 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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