Anti-MUC1-T1224 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15941
Gene Id	4582
Gene Symbols	MUC1
Protein Name / Synonyms	MUC1-T1224
Clonality	Polyclonal
Preparation	This MUC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1202-1231 amino acids from human MUC1.
Concentration (lot specific)	0.310 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

Specificity

Other Names

MUC1; PUM; Mucin-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; PEMT; Peanut-reactive urinary mucin; Polymorphic epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin; CD_antigen=CD227; Mucin-1 subunit alpha; Mucin-1 subunit beta; MUC1-CT

NCBI Accession #

NP_001018016.1;NP_001018017.1;NP_001037855.1;NP_001037856.1;NP_001037857.1;NP_001037858.1;NP_001191214.1;NP_001191215.1;NP_001191216.1;NP_001191217.1;NP_001191218.1;NP_001191219.1;NP_001191220.1;NP_00

Other Accession #

NP_001037856.1; NP_001037858.1; NP_002447.4; NP_001037855.1; NP_001018016.1; NP_001037857.1;

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

122102

Recommended Dilutions

WB: 1:1000

MUC1-T1224 Antibody (Cat# 102-10547) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the MUC1 antibody detected the MUC1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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