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Anti-MUC20 (C-term) Antibody

Catalog #: 102-17648

Rabbit Anti-Human MUC20 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q8N307
Gene Id
200958
Gene Symbols
MUC20
Protein Name / Synonyms
MUC20 (C-term)
ClonalityPolyclonal
PreparationThis MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human MUC20.
Concentration (lot specific)
0.330 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P, IF, FC
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names
MUC20; KIAA1359; Mucin-20
Other Accession #
Q86ST8

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
71982
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50; FC: 1:10-50
MUC20 Antibody (C-term) (Cat# 102-17648) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the MUC20 antibody detected the MUC20 protein (arrow).
MUC20 Antibody (C-term) (Cat# 102-17648)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MUC20 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of MUC20 Antibody (C-term)(Cat# 102-17648) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
MUC20 Antibody (C-term) (Cat# 102-17648) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.