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Anti-MUTED (Center) Antibody

Catalog #: 102-10562

Rabbit Anti-MUTED (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse
Host SpeciesRabbit
Accession Number
Q8TDH9
Gene Id
63915
Gene Symbols
BLOC1S5
Protein Name / Synonyms
MUTED (Center)
ClonalityPolyclonal
PreparationThis MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.

Specificity

Predicted Reactivity
Pig
Other Names
MUTED; Protein Muted homolog
NCBI Accession #
NP_001186251.1;NP_958437.1
Other Accession #
A5A777; NP_958437.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21609
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
MUTED Antibody (Center) (Cat# 102-10562) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow).
MUTED Antibody (Center) (Cat# 102-10562) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow).
MUTED Antibody (Center) (Cat# 102-10562) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MUTED Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.