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Anti-MUTYH (Center) Antibody
Catalog #: 102-18170
Rabbit Anti-MUTYH (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9UIF7 |
| Gene Id | 4595 |
| Gene Symbols | MUTYH |
| Protein Name / Synonyms | MUTYH (Center) |
| Clonality | Polyclonal |
| Preparation | This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, FC, IF |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Specificity
Other Names
MUTYH; MYH; A/G-specific adenine DNA glycosylase; MutY homolog
NCBI Accession #
NP_001041636.1;NP_001041637.1;NP_001041638.1;NP_001041639.1;NP_001121897.1;NP_036354.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
60069
Recommended Dilutions
WB: 1:1000; FC: 1:10-50; IF: 1:10-50
 | Western blot analysis of MUTYH Antibody (Center) (Cat# 102-18170) in mouse lung tissue lysates (35ug/lane). MUTYH (arrow) was detected using the purified Pab. |
 | MUTYH Antibody (Center) (Cat# 102-18170) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
 | Confocal immunofluorescent analysis of MUTYH Antibody (Center) (Cat# 102-18170) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.