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Anti-Myostatin (GDF8) (N-term) Antibody

Catalog #: 102-14963

Rabbit Anti-Human Myostatin (GDF8) (N-term) Antibody, 200 µl

Product Description

Specifications

Size200 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O14793
Gene Id
2660
Gene Symbols
MSTN
Protein Name / Synonyms
Myostatin (GDF8) (N-term)
ClonalityPolyclonal
PreparationThis Myostatin (GDF8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human Myostatin (GDF8).
Concentration (lot specific)
2.000 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Specificity

Predicted Reactivity
Bovine, Pig, Monkey
Other Names
MSTN; GDF8; Growth/differentiation factor 8; Myostatin
NCBI Accession #
NP_005250.1
Other Accession #
O18831; Q95J86; O18836

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42750
Recommended Dilutions
WB: 1:1000; IHC: 1:50
Western blot analysis of anti-GDF8 N-term Pab (Cat# 102-14963) in mouse liver tissue lysate. GDF8 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with GDF8 antibody (N-term )(Cat# 102-14963), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.