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Anti-NAMPT (Center) Antibody
Catalog #: 102-18116
Rabbit Anti-Human NAMPT (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P43490 |
| Gene Id | 10135 |
| Gene Symbols | NAMPT |
| Protein Name / Synonyms | NAMPT (Center) |
| Clonality | Polyclonal |
| Preparation | This NAMPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the Central region of human NAMPT. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Specificity
Predicted Reactivity
Mouse, Rat, Pig
Other Names
NAMPT; PBEF; PBEF1; Nicotinamide phosphoribosyltransferase; Pre-B-cell colony-enhancing factor 1; Visfatin
NCBI Accession #
NP_005737.1
Other Accession #
Q80Z29; Q52I78; Q99KQ4
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
55521
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of NAMPT Antibody (Center) (Cat# 102-18116) in A375 cell line lysates (35ug/lane). NAMPT (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human skeletal muscle reacted with NAMPT Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.