Anti-Natriuretic Peptide Receptor A (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P16066
Gene Id	4881
Gene Symbols	NPR1
Protein Name / Synonyms	Natriuretic Peptide Receptor A (N-term)
Clonality	Polyclonal
Preparation	This Natriuretic Peptide Receptor A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Natriuretic Peptide Receptor A.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	IHC-P
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.

Specificity

Other Names

NPR1; ANPRA; Atrial natriuretic peptide receptor 1; Atrial natriuretic peptide receptor type A; Guanylate cyclase A

NCBI Accession #

NP_000897.3

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

118919

Recommended Dilutions

IHC: 1:10-50

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Natriuretic Peptide Receptor A (NPR1/ANPA) antibody (N-term) (Cat# 102-17808), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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