Anti-NCK2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O43639
Gene Id	8440
Gene Symbols	NCK2
Protein Name / Synonyms	NCK2 (N-term)
Clonality	Polyclonal
Preparation	This NCK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human NCK2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specificity

Other Names

NCK2; GRB4; Cytoplasmic protein NCK2; Growth factor receptor-bound protein 4; NCK adaptor protein 2; SH2/SH3 adaptor protein NCK-beta

NCBI Accession #

NP_001004720.1;NP_003572.2

Other Accession #

NP_001004720.1; NP_003572.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

42915

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	NCK2 Antibody (N-term) (Cat# 102-12311) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the NCK2 antibody detected the NCK2 protein (arrow).
	NCK2 Antibody (N-term) (102-12311)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NCK2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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