Anti-NeuroD1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	Q13562
Gene Id	4760
Gene Symbols	NEUROD1
Protein Name / Synonyms	NeuroD1 (C-term)
Clonality	Polyclonal
Preparation	This NeuroD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-348 amino acids from the C-terminal region of human NeuroD1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Neuroscience
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

Specificity

Other Names

NEUROD1; BHLHA3; NEUROD; Neurogenic differentiation factor 1; Class A basic helix-loop-helix protein 3

NCBI Accession #

NP_002491.2

Other Accession #

Q64289; Q60867

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

39920

Recommended Dilutions

WB: 1:1000

NeuroD1 Antibody (I333) (Cat# 102-14598) western blot analysis in Y79 cell line ,mouse cerebellum and rat brain tissue lysates (35ug/lane).This demonstrates the NeuroD1 antibody detected the NeuroD1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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