Anti-Neurogenin1 (NeuroG1) (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q92886
Gene Id	4762
Gene Symbols	NEUROG1
Protein Name / Synonyms	Neurogenin1 (NeuroG1) (N-term)
Clonality	Polyclonal
Preparation	This Neurogenin1 (NeuroG1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Neurogenin1 (NeuroG1).
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Neuroscience
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.

Specificity

Other Names

NEUROG1; BHLHA6; NEUROD3; NGN; NGN1; Neurogenin-1; Class A basic helix-loop-helix protein 6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3

NCBI Accession #

NP_006152.2

Other Accession #

NP_006152

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

25718

Recommended Dilutions

WB: 1:1000

The anti-NeuroG1 N-term Pab (Cat#AP2022b) is used in Western blot to detect NeuroG1 in A375 cell lysate.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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