Anti-Neurokinin A Antibody

Neurokinin A, formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene. Neurokinin A has many excitatory effects on mammalian nervous systems and is also influential on the mammalian inflammatory and pain responses. Neurokinin A is present in excitatory neurons and secretory cells of the hypothalamic–pituitary–adrenal axis. Additionally, neurokinin A is found in the neurosensory system and modulates a wide range of inflammatory and tissue repairing processes. Inflammation, tissue healing and cell proliferation has been linked to neurokinin A release into surrounding tissues.

This antibody specifically binds to human Neurokinin A. Cross reactivity with mouse and rat Neurokinin A was not tested.

Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C. Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.