Anti-NKIRAS2 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NYR9
Gene Id	28511
Gene Symbols	NKIRAS2
Protein Name / Synonyms	NKIRAS2 (Center)
Clonality	Polyclonal
Preparation	This NKIRAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human NKIRAS2.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB (By similarity).

Specificity

Predicted Reactivity

Mouse, Chicken, Xenopus

Other Names

NKIRAS2; KBRAS2; NF-kappa-B inhibitor-interacting Ras-like protein 2; I-kappa-B-interacting Ras-like protein 2

NCBI Accession #

NP_001001349.1;NP_001138399.1;NP_001138400.1;NP_001138401.1;NP_060065.2

Other Accession #

Q32NS2; Q9CR56; Q5ZJW6; NP_060065.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

21508

Recommended Dilutions

WB: 1:1000

NKIRAS2 Antibody (Center) (Cat# 102-13027) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the NKIRAS2 antibody detected the NKIRAS2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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