Rabbit Anti-Mouse Nlk (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O54949 |
| Gene Id | 18099 |
| Gene Symbols | NLK |
| Protein Name / Synonyms | Nlk (C-term) |
| Clonality | Polyclonal |
| Preparation | This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Specificity
Predicted Reactivity
Rat, Bovine
Other Names
Nlk; Serine/threonine-protein kinase NLK; Nemo-like kinase
NCBI Accession #
NP_032728.3
Other Accession #
D3ZSZ3; Q9UBE8; E1BMN8; NP_032728.3; XP_001472539.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
58313
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Mouse Nlk Antibody (C-term) (Cat# 102-12223) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Nlk antibody detected the Nlk protein (arrow). |
 | Mouse Nlk Antibody (C-term) (Cat# 102-12223) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Nlk antibody detected the Nlk protein (arrow). |
 | Mouse Nlk Antibody (C-term) (102-12223)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Nlk Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.