Anti-NLRP12 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P59046
Gene Id	91662
Gene Symbols	NLRP12
Protein Name / Synonyms	NLRP12 (N-term)
Clonality	Polyclonal
Preparation	This NLRP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-212 amino acids from the N-terminal region of human NLRP12.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.

Specificity

Other Names

NLRP12; NALP12; PYPAF7; RNO; NACHT, LRR and PYD domains-containing protein 12; Monarch-1; PYRIN-containing APAF1-like protein 7; Regulated by nitric oxide

NCBI Accession #

NP_001264055.1;NP_001264058.1;NP_653288.1

Other Accession #

NP_653288.1; NP_150639.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

120173

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	NLRP12 Antibody (N-term) (Cat# 102-12258) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the NLRP12 antibody detected the NLRP12 protein (arrow).
	NLRP12 Antibody (N-term) (102-12258)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NLRP12 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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