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Anti-NUP50 (C-term) Antibody
Catalog #: 102-14154
Rabbit Anti-NUP50 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9UKX7 |
| Gene Id | 10762 |
| Gene Symbols | NUP50 |
| Protein Name / Synonyms | NUP50 (C-term) |
| Clonality | Polyclonal |
| Preparation | This NUP50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-461 amino acids from the C-terminal region of human NUP50. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.
Specificity
Predicted Reactivity
Rat
Other Names
NUP50; NPAP60L; Nuclear pore complex protein Nup50; 50 kDa nucleoporin; Nuclear pore-associated protein 60 kDa-like; Nucleoporin Nup50
NCBI Accession #
NP_009103.2;NP_705931.1
Other Accession #
O08587; Q9JIH2; Q8N6V5
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
50144
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of NUP50 (arrow) using rabbit polyclonal NUP50 Antibody (C-term) (RB08362). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NUP50 gene (Lane 2) (Origene Technologies). |
 | Western blot analysis of anti-NUP50 Pab (Cat# 102-14154) in mouse brain tissue lysate. NUP50(arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.