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Anti-OAS3 (C-term) Antibody
Catalog #: 102-16690
Rabbit Anti-Human OAS3 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9Y6K5 |
| Gene Id | 4940 |
| Gene Symbols | OAS3 |
| Protein Name / Synonyms | OAS3 (C-term) |
| Clonality | Polyclonal |
| Preparation | This OAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1056-1087 amino acids from the C-terminal region of human OAS3. |
| Concentration (lot specific) | 1.560 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
Specificity
Other Names
OAS3; 2'-5'-oligoadenylate synthase 3; p100 OAS
NCBI Accession #
NP_006178.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
121170
Recommended Dilutions
WB: 1:1000
 | The anti-OAS3 C-term Antibody (Cat# 102-16690) is used in Western blot to detect OAS3 in A375 lysate. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.