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Anti-OCT3/4 (C279) Antibody

Catalog #: 102-11139

Rabbit Anti-Human OCT3/4 (C279) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q01860
Gene Id
5460
Gene Symbols
POU5F1
Protein Name / Synonyms
OCT3/4 (C279)
ClonalityPolyclonal
PreparationThis OCT3/4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-297 amino acids from human OCT3/4.
Concentration (lot specific)
2.0 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Specificity

Other Names
POU5F1; OCT3; OCT4; OTF3; POU domain, class 5, transcription factor 1; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3
NCBI Accession #
NP_002692.2
Other Accession #
Q06416; NP_002692.2

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
38571
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
OCT3/4 Antibody (C279) (Cat# 102-11139) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the OCT3/4 antibody detected the OCT3/4 protein (arrow).
OCT3/4 Antibody (C279) (Cat# 102-11139)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OCT3/4 Antibody (C279) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.