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Anti-OTC (Center) Antibody
Catalog #: 102-17020
Rabbit Anti-Human OTC (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P00480 |
| Gene Id | 5009 |
| Gene Symbols | OTC |
| Protein Name / Synonyms | OTC (Center) |
| Clonality | Polyclonal |
| Preparation | This OTC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human OTC. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Pig
Other Names
OTC; Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase
NCBI Accession #
NP_000522.3
Other Accession #
P00481; O19072; P11725; Q9N1U7
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39935
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | OTC Antibody (Center) (Cat# 102-17020) western blot analysis in SW620 cell line and mouse liver?rat liver lysates (35ug/lane).This demonstrates the OTC antibody detected the OTC protein (arrow). |
 | Formalin-fixed and paraffin-embedded human hepatoarcinoma with OTC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Flow cytometric analysis of ATDC5 cells using OTC Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.