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Anti-PAAF1 (N-term) Antibody
Catalog #: 102-16395
Rabbit Anti-Human PAAF1 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9BRP4 |
| Gene Id | 80227 |
| Gene Symbols | PAAF1 |
| Protein Name / Synonyms | PAAF1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
Specificity
Predicted Reactivity
Bovine
Other Names
PAAF1; WDR71; Proteasomal ATPase-associated factor 1; Protein G-16; WD repeat-containing protein 71
NCBI Accession #
NP_001254732.1;NP_001254733.1;NP_001254734.1;NP_001254735.1;NP_079431.1
Other Accession #
Q148I1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42190
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of PAAF1 Antibody (N-term) (Cat# 102-16395) in A549 cell line lysates (35ug/lane).PAAF1 (arrow) was detected using the purified Pab. |
 | PAAF1 Antibody (N-term) (Cat# 102-16395) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAAF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.