Rabbit Anti-Human PAD4 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UM07 |
| Gene Id | 23569 |
| Gene Symbols | PADI4 |
| Protein Name / Synonyms | PAD4 (C-term) |
| Clonality | Polyclonal |
| Preparation | This PAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 512-544 amino acids from the C-terminal region of human PAD4. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation, Autoimmune Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.
Specificity
Other Names
PADI4; PADI5; PDI5; Protein-arginine deiminase type-4; HL-60 PAD; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV
NCBI Accession #
NP_036519.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
74079
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-PAD4 Pab (Cat# 102-15058) in 293 cell line lysate. PAD4(arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.