Rabbit Anti-PAK4 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O96013 |
| Gene Id | 10298 |
| Gene Symbols | PAK4 |
| Protein Name / Synonyms | PAK4 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4. |
| Concentration (lot specific) | 1.360 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Specificity
Other Names
PAK4; KIAA1142; Serine/threonine-protein kinase PAK 4; p21-activated kinase 4
NCBI Accession #
NP_001014831.1;NP_001014832.1;NP_001014834.1;NP_001014835.1;NP_005875.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
64072
Recommended Dilutions
IHC: 1:10-50; WB: 1:1000
 | Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PAK4 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | The anti-PAK4 Pab (Cat# 102-17704) is used in Western blot to detect PAK4 in mouse small intestine tissue lysate. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.