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Anti-PARP3 (N-term) Antibody
Catalog #: 102-14700
Rabbit Anti-Human PARP3 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9Y6F1 |
| Gene Id | 10039 |
| Gene Symbols | PARP3 |
| Protein Name / Synonyms | PARP3 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PARP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the N-terminal region of human PARP3. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Specificity
Other Names
PARP3;ADPRT3; ADPRTL3; Poly [ADP-ribose] polymerase 3; Poly [ADP-ribose] polymerase 3; ADP-ribosyltransferase diphtheria toxin-like 3; Poly [ADP-ribose] polymerase 3; IRT1; Poly [ADP-ribose] polymerase 3; NAD(+) ADP-ribosyltransferase 3; Poly [ADP-ribose] polymerase 3; Poly[ADP-ribose] synthase 3
NCBI Accession #
NP_001003931.2;NP_005476.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
60070
Recommended Dilutions
WB: 1:1000
 | PARP3 Antibody (N-term) (Cat# 102-14700) western blot analysis in K562,MDA-MB453,NCI-H292,A549,293,Hela,CEM,NCI-H460 cell line and human nomal uterus tissue lysates (35ug/lane).This demonstrates the PARP3 antibody detected the PARP3 protein (arrow). |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.