Anti-PBP (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P30086
Gene Id	5037
Gene Symbols	PEBP1
Protein Name / Synonyms	PBP (Center)
Clonality	Polyclonal
Preparation	This PBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-167 amino acids from the Central region of human PBP.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.

Specificity

Other Names

PEBP1; PBP; PEBP; Phosphatidylethanolamine-binding protein 1; HCNPpp; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; Hippocampal cholinergic neurostimulating peptide

NCBI Accession #

NP_002558.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

21057

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of anti-PBP Antibody (Center) Antibody (Center) (Cat# 102-17796) in 293 cell line lysates (35ug/lane). PBP(arrow) was detected using the purified Pab.
	Western blot analysis of anti-PBP Antibody (Center) (Cat# 102-17796) in mouse NIH-3T3 tissue lysates (35ug/lane). PBP(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
	Western blot analysis of PBP (arrow) using rabbit polyclonal PBP Antibody (A152) (Cat# 102-17796). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PBP gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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