Anti-PCNA (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Accession Number	P12004
Gene Id	5111
Gene Symbols	PCNA
Protein Name / Synonyms	PCNA (C-term)
Clonality	Monoclonal
Preparation	This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
Concentration (lot specific)	0.500 mg/ml
Recommended Applications	IHC-P, Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Specificity

Predicted Reactivity

Bovine, Humanamster, Monkey

Other Names

PCNA;Proliferating cell nuclear antigen; Proliferating cell nuclear antigen; Cyclin

NCBI Accession #

NP_002583.1;NP_872590.1

Other Accession #

P04961; P61258; P57761; Q3ZBW4

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

28769

Recommended Dilutions

WB: 1:2000

PCNA Antibody (C-term) (Cat# 102-10464) western blot analysis in Hela,mouse L929 and rat C6 cell line lysates (35ug/lane).This demonstrates the PCNA antibody detected the PCNA protein (arrow).

Antigen Source

Human

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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