Anti-PCPTP1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q15256
Gene Id	5801
Gene Symbols	PTPRR
Protein Name / Synonyms	PCPTP1 (N-term)
Clonality	Polyclonal
Preparation	This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 amino acids from the N-terminal region of human PCPTP1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.

Specificity

Other Names

PTPRR; ECPTP; PTPRQ; Receptor-type tyrosine-protein phosphatase R; Ch-1PTPase; NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1

NCBI Accession #

NP_001193944.1;NP_001193945.1;NP_002840.2;NP_570897.2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

73834

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	The anti-PCPTP1 Pab (Cat# 102-17859) is used in Western blot to detect PCPTP1 in placenta tissue lysate.
	Formalin-fixed and paraffin-embedded human brain tissue reacted with hPCPTP1-Y249, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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