Anti-PDCD6IP (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8WUM4
Gene Id	10015
Gene Symbols	PDCD6IP
Protein Name / Synonyms	PDCD6IP (Center)
Clonality	Polyclonal
Preparation	This PDCD6IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Specificity

Other Names

PDCD6IP; AIP1; ALIX; KIAA1375; Programmed cell death 6-interacting protein; ALG-2-interacting protein 1; Hp95

NCBI Accession #

NP_001155901.1;NP_037506.2

Other Accession #

NP_037506.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

96023

Recommended Dilutions

WB: 1:1000

PDCD6IP Antibody (Center) (Cat# 102-14499) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDCD6IP antibody detected the PDCD6IP protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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