Anti-PDGFRL (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q15198
Gene Id	5157
Gene Symbols	PDGFRL
Protein Name / Synonyms	PDGFRL (C-term)
Clonality	Polyclonal
Preparation	This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-357 amino acids from the C-terminal region of human PDGFRL.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

Specificity

Other Names

PDGFRL; PRLTS; Platelet-derived growth factor receptor-like protein; PDGF receptor beta-like tumor suppressor

NCBI Accession #

NP_006198.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

41861

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of anti-PDGFRL Antibody (C-term)(Cat# 102-17538) in Hela cell line lysates (35ug/lane).PDGFRL(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human colon carcinoma reacted with PDGFRL antibody (C-term) (Cat# 102-17538), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
	Western blot analysis of PDGFRL (arrow) using rabbit polyclonal PDGFRL-T343 (Cat# 102-17538). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PDGFRL gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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