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Anti-PDHA1 (Center) Antibody
Catalog #: 102-18342
Rabbit Anti-Human PDHA1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P08559 |
| Gene Id | 5160 |
| Gene Symbols | PDHA1 |
| Protein Name / Synonyms | PDHA1 (Center) |
| Clonality | Polyclonal |
| Preparation | This PDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human PDHA1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Pig, Monkey
Other Names
PDHA1; PHE1A; Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; PDHE1-A type I
NCBI Accession #
NP_000275.1;NP_001166925.1;NP_001166926.1;NP_001166927.1
Other Accession #
P26284; P29804; P35486; Q8HXW9; A7MB35
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
43296
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of PDHA1 Antibody (Center) (Cat# 102-18342) in Hela cell line lysates (35ug/lane). PDHA1 (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.