Anti-PDK4 (Center D98) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q16654
Gene Id	5166
Gene Symbols	PDK4
Protein Name / Synonyms	PDK4 (Center D98)
Clonality	Polyclonal
Preparation	This PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the Central region of human PDK4.
Concentration (lot specific)	2.000 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Specificity

Other Names

PDK4; PDHK4; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; Pyruvate dehydrogenase kinase isoform 4

NCBI Accession #

NP_002603.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

46469

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; IF: 1:10-50

	Western blot analysis of anti-PDK4 Antibody (Center D98) (Cat# 102-17094) in HL60 cell line lysates (35ug/lane).PDK4(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PDK4 antibody (Center D98) (Cat# 102-17094), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
	Confocal immunofluorescent analysis of PDK4 Antibody (Center D98)(Cat# 102-17094) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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