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Anti-PDZD3 (Center) Antibody
Catalog #: 102-13488
Rabbit Anti-Human PDZD3 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q86UT5 |
| Gene Id | 79849 |
| Gene Symbols | PDZD3 |
| Protein Name / Synonyms | PDZD3 (Center) |
| Clonality | Polyclonal |
| Preparation | This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).
Specificity
Other Names
PDZD3; IKEPP; NHERF4; PDZK2; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Intestinal and kidney-enriched PDZ protein; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4
NCBI Accession #
NP_001161940.1;NP_079067.3
Other Accession #
NP_001161940.1; NP_079067.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
61032
Recommended Dilutions
WB: 1:1000
 | PDZD3 Antibody (Center) (Cat# 102-13488) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDZD3 antibody detected the PDZD3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.