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Anti-PEDF / SERPINF1 Antibody
Catalog #: 130-10194
Mouse Anti-Recombinant Human PEDF / SERPINF1 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Accession Number | P36955 |
| Gene Id | 5176 |
| Gene Symbols | SERPINF1 PEDF PIG35 |
| Clonality | Monoclonal |
| Immunogen | Immunogen was recombinant protein. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgM fraction of tissue culture supernatant was purified by HiTrap IgM Purification HP. |
| Recommended Applications | ELISA (recommended work dilution= 1:10, 000), Western Blotting (recommended work dilution= 1:1, 000-5, 000), |
| Antigen Catalog Number | 230-00223 |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Research Area | Angiogenesis |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as choroidal neovascularization, heart disease, and cancer. In humans, pigment epithelium-derived factor is encoded by the SERPINF1 gene.
Specificity
This antibody binds to its immunogen, and did not show any cross reactivity with unrelated antigens in ELISA. Cross reactivity with mouse and rat SERPIN F1 has not been tested yet.
Storage
Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -113°C. After reconstitution, it can be aliquoted and storedtory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium.
Expiration:
12 months from the date of shipment when stored properly.