Anti-PEMT (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9UBM1
Gene Id	10400
Gene Symbols	PEMT
Protein Name / Synonyms	PEMT (N-term)
Clonality	Polyclonal
Preparation	This PEMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PEMT.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.

Specificity

Other Names

PEMT; PEMPT; PNMT; Phosphatidylethanolamine N-methyltransferase; PEMT2

NCBI Accession #

NP_001254480.1;NP_001254481.1;NP_009100.2;NP_680477.1;NP_680478.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22134

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of anti-PEMT Antibody (N-term) Pab (Cat# 102-10609) in mouse kidney tissue lysates (35ug/lane). PEMT(arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PEMT antibody (N-term) (Cat# 102-10609), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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