Anti-PGR/PR (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	P06401
Gene Id	5241
Gene Symbols	PGR
Protein Name / Synonyms	PGR/PR (Ascites)
Clonality	Monoclonal
Preparation	This PGR/PR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from human PGR/PR.
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

Specificity

Other Names

PGR; NR3C3; Progesterone receptor; Nuclear receptor subfamily 3 group C member 3

NCBI Accession #

NP_000917.3;NP_001189403.1;NP_001258091.1

Other Accession #

NP_000917.3

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

98981

Recommended Dilutions

WB: 1:100-3200

PGR/PR Antibody (Cat# 102-10192) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the PGR/PR antibody detected the PGR/PR protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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