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Anti-PGR/PR (Center) Antibody
Catalog #: 102-11849
Rabbit Anti-Human PGR/PR (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P06401 |
| Gene Id | 5241 |
| Gene Symbols | PGR |
| Protein Name / Synonyms | PGR/PR (Center) |
| Clonality | Polyclonal |
| Preparation | This PGR/PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of human PGR/PR. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.
Specificity
Other Names
PGR; NR3C3; Progesterone receptor; Nuclear receptor subfamily 3 group C member 3
NCBI Accession #
NP_000917.3;NP_001189403.1;NP_001258091.1
Other Accession #
NP_000917.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
98981
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | PGR/PR Antibody (Center) (Cat# 102-11849) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PGR/PR antibody detected the PGR/PR protein (arrow). |
 | PGR/PR Antibody (Center) (Cat# 102-11849)immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PGR/PR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.