Rabbit Anti-Human Phospho-ABL(Y412) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P00519 |
| Gene Id | 25 |
| Gene Symbols | ABL1 |
| Protein Name / Synonyms | Phospho-ABL(Y412) |
| Clonality | Polyclonal |
| Preparation | This ABL Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y412 of human ABL. |
| Concentration (lot specific) | 0.340 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, Dot Blotting |
| Research Area | Angiogenesis, Cardiovascular Disease, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells.
Specificity
Predicted Reactivity
Mouse
Other Names
ABL1; ABL; JTK7; Tyrosine-protein kinase ABL1; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150
NCBI Accession #
NP_005148.2;NP_009297.2
Other Accession #
Q4JIM5; P42684; P00520
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
122873
Recommended Dilutions
WB: 1:1000; DB: 1:500; IHC: 1:50-100
 | Western blot analysis of Phospho-ABL-Y412 Antibody Pab (Cat# 102-15261) in A2058 cell line lysate (35ug/lane). ABL (arrow) was detected using the purified Pab. |
 | Dot blot analysis of ABL-Y412 Phospho-specific Pab (Cat# 102-15261) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.