Anti-Phospho-ACK1 (Y826) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q07912
Gene Id	10188
Gene Symbols	TNK2
Protein Name / Synonyms	Phospho-ACK1(Y826)
Clonality	Polyclonal
Preparation	This ACK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y826 of human ACK1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Dot Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

TNK2; ACK1; Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2

NCBI Accession #

NP_001010938.1;NP_005772.3

Other Accession #

Q5U2X5; O54967; Q17R13

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

114569

Recommended Dilutions

DB: 1:500

Dot blot analysis of anti-Phospho-ACK1-pY826 Phospho-specific Pab (Cat# 102-15525) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products