Anti-Phospho-bcl-2 (S70) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P10415
Gene Id	596
Gene Symbols	BCL2
Protein Name / Synonyms	Phospho-bcl-2(S70)
Clonality	Polyclonal
Preparation	This bcl-2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S70 of human bcl-2.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting, Dot Blotting
Research Area	Apoptosis, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].

Specificity

Other Names

BCL2; Apoptosis regulator Bcl-2

NCBI Accession #

NP_000624.2

Other Accession #

NP_000624.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

26266

Recommended Dilutions

DB: 1:500; WB: 1:1000

	Dot blot analysis of Phospho-bcl-2-S70 Antibody Phospho-specific Pab (Cat# 102-15649) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
	Western blot analysis of extracts from Jurkat cells,untreated or treated with paclitaxel,using phospho-Bcl2(Ser70)(left) or Bcl2 antibody(right).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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