Rabbit Anti-Human Phospho-Bik(T33) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13323 |
| Gene Id | 638 |
| Gene Symbols | BIK |
| Protein Name / Synonyms | Phospho-Bik(T33) |
| Clonality | Polyclonal |
| Preparation | This Bik Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T33 of human Bik. |
| Concentration (lot specific) | 0.330 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Specificity
Other Names
BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4
NCBI Accession #
NP_001188.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
18016
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-Bik Pab (Cat# 102-15274) in mouse liver tissue lysate (35ug/lane). Bik(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.