Anti-Phospho-Cdc25A (S79) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P30304
Gene Id	993
Gene Symbols	CDC25A
Protein Name / Synonyms	Phospho-Cdc25A(S79)
Clonality	Polyclonal
Preparation	This Cdc25A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S79 of human Cdc25A.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Dot Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

CDC25A is a member of the CDC25 family of phosphatases.CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A

NCBI Accession #

NP_001780.2;NP_963861.1

Other Accession #

P48965; P48964; A7MBD1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

59087

Recommended Dilutions

DB: 1:500

Dot blot analysis of anti-Cdc25A Phospho-specific Pab (Cat# 102-15461) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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