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Anti-Phospho-IRF3-S396 Antibody

Catalog #: 144-50755

Phospho-IRF3-S396 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
Q14653
Gene Id
3661
Gene Symbols
IRF3
Protein Name / Synonyms
IRF3, IIAE7, interferon regulatory factor 3
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaInflammation
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
12kDa/16kDa/33kDa/47kDa/49kDa
Observed MW
55kDa

Immunogen

A phospho specific peptide corresponding to residues surrounding S396 of human IRF3

Modification

Phospho S396

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.