Anti-Phospho-JMJD2B (S566) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O94953
Gene Id	23030
Gene Symbols	KDM4B
Protein Name / Synonyms	Phospho-JMJD2B(S566)
Clonality	Polyclonal
Preparation	This JMJD2B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S566 of human JMJD2B.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Dot Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Specificity

Other Names

KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B

NCBI Accession #

NP_055830.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

121897

Recommended Dilutions

DB: 1:500

Dot blot analysis of anti-Phospho-JMJD2B-S566 Phospho-specific Pab (Cat# 102-15555) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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