Anti-Phospho-KIT (T274) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P10721
Gene Id	3815
Gene Symbols	KIT
Protein Name / Synonyms	Phospho-KIT(T274)
Clonality	Polyclonal
Preparation	This KIT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T274 of human KIT.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Dot Blotting
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

KIT; SCFR; Mast/stem cell growth factor receptor Kit; Piebald trait protein; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD_antigen=CD117; Flags: Precursor

NCBI Accession #

NP_000213.1;NP_001087241.1

Other Accession #

NP_000213.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

109865

Recommended Dilutions

DB: 1:500

Dot blot analysis of Phospho-KIT-T274 Antibody Phospho-specific Pab (Cat# 102-15615) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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