Anti-Phospho-MAP3K7 (S192) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O43318
Gene Id	6885
Gene Symbols	MAP3K7
Protein Name / Synonyms	Phospho-MAP3K7(S192)
Clonality	Polyclonal
Preparation	This MAP3K7 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S192 of human MAP3K7.
Concentration (lot specific)	0.491 mg/ml
Recommended Applications	Dot Blotting
Research Area	Cardiovascular Disease, Cancer, Inflammation, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine

Other Names

MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1

NCBI Accession #

NP_003179.1;NP_663304.1;NP_663305.1;NP_663306.1

Other Accession #

P0C8E4; Q62073; A2VDU3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

67196

Recommended Dilutions

DB: 1:500

Dot blot analysis of Phospho-MAP3K7-S192 polyclonal antibody (Cat# 102-15393) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5ug per ml. P-Pab: phospho-antibody; P-Peptide: phospho-peptide; NP-Peptide: non-phospho-peptide.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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