Anti-Phospho-MAPKAPK2 (S272) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P49137
Gene Id	9261
Gene Symbols	MAPKAPK2
Protein Name / Synonyms	Phospho-MAPKAPK2(S272)
Clonality	Polyclonal
Preparation	This MAPKAPK2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2.
Concentration (lot specific)	0.480 mg/ml
Recommended Applications	Dot Blotting, IHC-P
Research Area	Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Specificity

Predicted Reactivity

Mouse, Rabbit

Other Names

MAPKAPK2; MAP kinase-activated protein kinase 2

NCBI Accession #

NP_004750.1;NP_116584.2

Other Accession #

P49139; P49138

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

45568

Recommended Dilutions

DB: 1:500; IHC: 1:50-100

	Dot blot analysis of anti-Phospho-MAPKAPK2-S272 Antibody (Cat# 102-15313) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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