Rabbit Anti-Human Phospho-MYC(T58) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P01106 |
| Gene Id | 4609 |
| Gene Symbols | MYC |
| Protein Name / Synonyms | Phospho-MYC(T58) |
| Clonality | Polyclonal |
| Preparation | This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC. |
| Concentration (lot specific) | 0.470 mg/ml |
| Recommended Applications | Western Blotting, Dot Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
Specificity
Predicted Reactivity
Mouse, Rat, Zebrafish, Bovine, Chicken, Pig, Xenopus
Other Names
MYC; BHLHE39; Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; Proto-oncogene c-Myc; Transcription factor p64
NCBI Accession #
NP_002458.2
Other Accession #
P09416; Q29031; P01108; P01109; Q2HJ27; P24793; Q63379; P03966; P04198; Q9PSJ0; P18444; P15171; Q7ZVS9; P52160; P06171
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
48804
Recommended Dilutions
DB: 1:500; WB: 1:1000
 | Dot blot analysis of Phospho-MYC-T58 Pab (Cat.102-15386) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
 | Western blot analysis of Phospho-MYC-T58 Antibody in human TPA activated Hela cell line lysates. Phospho-MYC (arrow) was detected using the purified PAb. (0: without TPA; 1: 60ug/ml TPA, 15min; 2: 60ug/ml TPA, 30min; 3: 60ug/ml TPA, 45min; 4: 125ug/ml TPA, 15min; 5: 125ug/ml TPA, 30min; 6: 125ug/ml TPA, 45min; 7: 250ug/ml TPA, 15min; 8: 250ug/ml TPA, 30min; 9: 250ug/ml, 45min) |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.