Anti-Phospho-Nephrin (Y1210)) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O60500
Gene Id	4868
Gene Symbols	NPHS1
Protein Name / Synonyms	Phospho-Nephrin(Y1210))
Clonality	Polyclonal
Preparation	This Nephrin Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1210 of human Nephrin.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Dot Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

Specificity

Other Names

NPHS1; NPHN; Nephrin; Renal glomerulus-specific cell adhesion receptor

NCBI Accession #

NP_004637.1

Other Accession #

NP_004637.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

134742

Recommended Dilutions

DB: 1:500

Dot blot analysis of anti-Phospho-Nephrin (Y1210) antibody Phospho-specific Pab (Cat# 102-15548) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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