Rabbit Anti-Human Phospho-PAK1(T423) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13153 |
| Gene Id | 5058 |
| Gene Symbols | PAK1 |
| Protein Name / Synonyms | Phospho-PAK1(T423) |
| Clonality | Polyclonal |
| Preparation | This PAK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T423 of human PAK1. |
| Concentration (lot specific) | 0.460 mg/ml |
| Recommended Applications | Western Blotting, IF, Dot Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Rabbit, Xenopus
Other Names
PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; p65-PAK
NCBI Accession #
NP_001122092.1;NP_002567.3
Other Accession #
Q8AXB4; Q62829; Q61036; O75914; Q64303; Q29502; Q8CIN4; Q13177; P35465; O88643; Q08E52
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
60647
Recommended Dilutions
IF: 1:10-50; DB: 1:500
 | Confocal immunofluorescent analysis of Phospho-PAK1-pT423 Antibody(Cat# 102-15415) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | Dot blot analysis of anti-PAK1-pT423 Phospho-specific Pab (Cat# 102-15415) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.