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Anti-Phospho-PLB (T17) Antibody

Catalog #: 102-15522

Rabbit Anti-Human Phospho-PLB(T17) Antibody, 200 µl

Product Description

Specifications

Size200 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P26678
Gene Id
5350
Gene Symbols
PLN
Protein Name / Synonyms
Phospho-PLB(T17)
ClonalityPolyclonal
PreparationThis PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting, Dot Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Specificity

Other Names
PLN; PLB; Cardiac phospholamban
NCBI Accession #
NP_002658.1

Format

Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
6109
Recommended Dilutions
DB: 1:500
Dot blot analysis of anti-Phospho-PLB-T17 Phospho-specific Pab (Cat# 102-15522) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.