Rabbit Anti-Human Phospho-RAD9(S277) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q99638 |
| Gene Id | 5883 |
| Gene Symbols | RAD9A |
| Protein Name / Synonyms | Phospho-RAD9(S277) |
| Clonality | Polyclonal |
| Preparation | This RAD9 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S277 of human RAD9. |
| Concentration (lot specific) | 0.320 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Rad9 is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade.
Specificity
Predicted Reactivity
Monkey
Other Names
RAD9A; Cell cycle checkpoint control protein RAD9A; DNA repair exonuclease rad9 homolog A
NCBI Accession #
NP_001230153.1;NP_004575.1
Other Accession #
Q4R5X9
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42547
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | The anti-Phospho-Rad9-S277 Pab (Cat# 102-15340) is used in Western blot to detect Phospho-Rad9-S277 in Y79 tissue lysate |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.